Development and characterization of an equine infectious anemia virus Env-pseudotyped reporter virus.

نویسندگان

  • R L Tallmadge
  • M A Brindley
  • J Salmans
  • R H Mealey
  • W Maury
  • S Carpenter
چکیده

We developed a replication-defective reporter virus pseudotyped with the envelope glycoprotein of equine infectious anemia virus (EIAV). The in vitro host range and neutralization phenotype of EIAV Env-pseudotyped virus were similar to those of replication-competent virus. An EIAV Env pseudovirus will improve antigenic characterization of viral variants and evaluation of lentivirus vaccines.

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عنوان ژورنال:
  • Clinical and vaccine immunology : CVI

دوره 15 7  شماره 

صفحات  -

تاریخ انتشار 2008